1. Browse Species

On the Home page, you can see all available species. Click on a species card to view its protein-protein interaction predictions.

2. Search Proteins

On each species page, use the search bar to find specific proteins. You can:

  • Search for a single protein ID (e.g., AT1G01010.1) to find all interactions involving that protein.
  • Search for a pair (e.g., AT1G01010.1,AT1G01020.1) to find a specific interaction.
  • Use partial protein IDs for broader search results.

3. Filter Results

Use the filter controls to narrow down results:

  • Prediction filter: Show only positive or negative predictions.
  • Probability threshold: Set a minimum ensemble probability.

4. View Protein Details

Click on any protein ID in the results table to view its details, including sequence information and interaction partners.

5. Interpretability

Click the "View" button in the Interpretability column to see residue-level attention weights for a protein pair. The attention visualization shows which residues are most important for the predicted interaction, with options for different color schemes and attention head selection.

6. Downloads

When available, PDB structure files and other data can be downloaded from the Downloads section on each species page.

Data Description

Field Description
Protein 1 / Protein 2 Identifiers of the two proteins in the predicted interaction pair.
Ensemble Probability The combined prediction score from all models (0-1). Higher values indicate stronger predicted interaction.
Prediction Binary classification: Positive (predicted to interact) or Negative.
Model Details Individual model probabilities and their ensemble weights.
Attention Weights Per-residue importance scores from the SEPAL attention mechanism.